Pasteur Institute: Timeline of key events

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A French chemist and microbiologist, Pasteur helped develop a method to slow the development of microbes in milk and wine called pasteurisation. He also pioneered the first vaccine against rabies.1822-12-27T00:00:00+0000Mechnikov discovered phagocytes (macrophages), which are a major defence mechanism in the immune system. 1845-05-16T00:00:00+0000Laveran shared the 1907 Nobel Prize for Medicine for identifying protozoan as the cause of malaria. 1845-06-18T00:00:00+0000Bordet won the 1919 Nobel Prize for Medicine for working out how white blood cells engulf bacteria to fight infections and red blood cells break open to release haemoglobin into blood plasma. His work also laid the foundation for the development of serological tests for syphilis. 1870-06-13T00:00:00+0000d'Herelle was a microbiologist who co-discovered bacteriophages, viruses that infect bacteria.1873-04-25T00:00:00+0000Louis Pasteur develops an attenuated chicken cholera vaccine1879-01-01T00:00:00+0000Louis Pasteur successfully tested his rabies vaccine on a nine year old boy who had been bitten by a rabid dog.1885-07-06T00:00:00+0000Jules Bordet, a Belgian immunologist and microbiologist, on the basis of experiments heating fresh serum containing antibacterial antibodies, detects the presence of a substance, initially called alexin or complement which appears to act as an accessory to antibodies, taking on the role of destroying antigens.1895-01-01T00:00:00+0000A French chemist and microbiologist, Pasteur helped develop a method to slow the development of microbes in milk and wine called pasteurisation. He also pioneered the first vaccine against rabies.1895-09-28T00:00:00+0000Lwoff shared the 1965 Nobel Prize for Medicine for 'discoveries concerning genetic control of enzyme and virus synthesis'.1902-05-08T00:00:00+0000Mechnikov discovered phagocytes (macrophages), which are a major defence mechanism in the immune system. 1916-07-15T00:00:00+0000Monod shared the 1965 Nobel Prize for Medicine for 'discoveries concerning genetic control of enzyme and virus synthesis.'1920-06-07T00:00:00+0000Jacob shared the 1965 Nobel Prize for Medicine for 'discoveries concerning genetic control of enzyme and virus synthesis.' 1920-06-17T00:00:00+0000Laveran shared the 1907 Nobel Prize for Medicine for identifying protozoan as the cause of malaria. 1922-05-18T00:00:00+0000Roger Vendrely, Colette Vendrely and Andre Boivin, French scientists, report that the DNA content of cells is directly related to the chromosomes they contain. Importantly they discover half as much DNA in the nuclei of sex cells as they find in body cells. This provides further evidence for the fact that DNA is genetic material. 1949-01-01T00:00:00+0000d'Herelle was a French Canadian microbiologist who co-discovered bacteriophages, viruses that infect bacteria.1949-02-22T00:00:00+0000Bordet was a Belgian immunologist who the 1919 Nobel Prize for Medicine for working out how white blood cells engulf bacteria to fight infections and red blood cells break open to release haemoglobin into blood plasma. His work also laid the foundation for the development of serological tests for syphilis. 1961-04-06T00:00:00+0000Monod shared the 1965 Nobel Prize for Medicine for 'discoveries concerning genetic control of enzyme and virus synthesis.'1976-05-31T00:00:00+0000A French microbiologist, Lwoff is best known for discovering genetic control enzymes and virus synthesis. He showed that bacteria can pass viruses on to subsequent bacterial generations following initial infection. Lwoff also discovered that vitamins help promote growth in microbes and can serve as co-enzymes. 1994-09-30T00:00:00+0000Jacob shared the 1965 Nobel Prize for Medicine for 'discoveries concerning genetic control of enzyme and virus synthesis.' 2013-04-19T00:00:00+0000
Date Event People Places Sciences
27 Dec 1822Louis Pasteur was bornPasteurPasteur InstituteBacteriology
16 May 1845Ilya Ilyich Mechnikov was born in Kharkov (now Kharkiv), Russian Empire (now Ukraine)MechnikovPasteur InstituteImmunology
18 Jun 1845Charles L Alphonse Laveran was born in Paris, FranceLaveranPasteur InstituteInfectious diseases
13 Jun 1870Jules Bordet was born in Soignies, BelgiumBordetPasteur InstituteImmunology
25 Apr 1873Felix d'Herelle was born in Montreal, Canadad'HerellePasteur InstituteBacteriology, Virology
1879Chicken cholera vaccine developedPasteurPasteur InstituteBacteriology, Vaccine
1885First rabies vaccine testedPasteurPasteur InstituteBacteriology, Vaccine
1895Complement detected to be an accessory to antibodiesBordetPasteur InstituteAntibodies
28 Sep 1895Louis Pasteur diedPasteurPasteur InstituteBacteriology, Vaccine
8 May 1902Andre Lwoff was born in Ainay-le-Chateau, FranceLwoffPasteur InstituteMicrobiology, Virology
15 Jul 1916Ilya Ilyich Mechnikov diedMechnikovPasteur InstituteImmunology
7 Jun 1920Jacques Monod was born in Nancy, FranceMonodPasteur InstituteGenetics
17 Jun 1920Francois Jacob was born in Nancy, FranceJacobPasteur InstituteGenetics
18 May 1922Charles L Alphonse Laveran diedLaveranPasteur Institute 
1949DNA content of a cells linked to a cell's number of chromosomesVendrely, BoivinPasteur Institute, Strasbourg School of MedicineDNA
22 Feb 1949Felix d'Herelle diedd'HerellePasteur InstituteBacteriology, Virology
6 Apr 1961Jule Bordet diedBordetPasteur InstituteImmunology
31 May 1976Jacques Monod diedMonodPasteur InstituteGenetics
30 Sep 1994Andre Michel Lwoff diedLwoffPasteur InstituteMicrobiology, Virology
19 Apr 2013Francois Jacob diedJacobPasteur InstituteGenetics

27 Dec 1822

Louis Pasteur was born

16 May 1845

Ilya Ilyich Mechnikov was born in Kharkov (now Kharkiv), Russian Empire (now Ukraine)

18 Jun 1845

Charles L Alphonse Laveran was born in Paris, France

13 Jun 1870

Jules Bordet was born in Soignies, Belgium

25 Apr 1873

Felix d'Herelle was born in Montreal, Canada

1879

Chicken cholera vaccine developed

1885

First rabies vaccine tested

1895

Complement detected to be an accessory to antibodies

28 Sep 1895

Louis Pasteur died

8 May 1902

Andre Lwoff was born in Ainay-le-Chateau, France

15 Jul 1916

Ilya Ilyich Mechnikov died

7 Jun 1920

Jacques Monod was born in Nancy, France

17 Jun 1920

Francois Jacob was born in Nancy, France

18 May 1922

Charles L Alphonse Laveran died

1949

DNA content of a cells linked to a cell's number of chromosomes

22 Feb 1949

Felix d'Herelle died

6 Apr 1961

Jule Bordet died

31 May 1976

Jacques Monod died

30 Sep 1994

Andre Michel Lwoff died

19 Apr 2013

Francois Jacob died